???? ??? ?????? ???? ???? ??? ????? . ???? ?? ??? ???? ?? ????? . ??? ??????? ???????? ?????? ?????? ??? ???? ??????? ?? ???? ??? ??????? ??? ??? ???????? ??? ??????? ?? ??? ????? ?????? ??? ????? ?????? ???? ???? ????? ??? ?????? ???? ?? ???????? ????? ???? ??? ???? ????? ??? ?????? ??? ??? ??? ???? ???? ????? ??????Only one?third in the dose is o